Reference Sheet: Rhabdomyolysis

SO WHAT IS RHABDOMYOLYSIS ANYWAYS?

Rhabdomyolysis is the breakdown of muscle tissue due to some type of direct or indirect injury to the muscle. Some potential causes of rhabdomyolysis: fall, crush injury, prolonged immobilization, seizures, low phosphate levels, and or use of cholesterol lowering medications called “statins” etc.

The contents of the muscle fibers are released into the blood stream. The protein that is released is called myoglobin. Myoglobin is hard on the kidneys. Thus, kidney failure is often seen. Aggressive IV fluid hydration, addressing the causative agent(s), and monitoring labs values closely, are the key interventions to helping reverse the harmful effects of rhabdomyolysis. Often a nephrologist is also consulted to follow along for specific recommendations.

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DISCLAIMER: The information posted is not intended to be medical advice. Check with your primary care provider regarding questions about your health. This post and all other posts are for educational purposes only. This information is intended for medical professionals & students. This is not intended to guide in medical decisions or treatment in any way. As always, medical professionals should call the on call provider if any clarifications are needed. State and hospital protocols should always be followed accordingly. Med Made Ez (MME) disclaims any liability for the decisions you make based on this information.

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