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TODAY’S TEST QUESTION:
CORRECT ANSWER:
A) Clindamycin
MORE INFO:
- Clindamycin is more likely to cause c-diff than the other antibiotics listed here.
- Flagyl is actually used to treat clostridium difficile aka c-diff.
- Vancomycin also used to treat, but has to be PO not IV
- Sulfonamides (bactrim), trimethroprim, and macrolides, occasionally cause c-diff, but not as often as fluroquinolones, clindamycin, PCN, and cephalosporins.
- Aminoglycosides and tetracyclines rarely cause c-diff.
- Clindmaycin is notorious for causing c-diff.
- Taking probiotics with any antibiotic is extremely helpful when trying to prevent c-diff. Note that when c-diff is related to antibiotic use, signs and symptoms of c-diff usually develop within 10 days after antibiotic use.
- When an individual has severe c-diff they can have 10-15+ watery stools a day, abdominal cramping, fever, and dehydration (2)
Reference:
- Up to date-Patient education: Antibiotic-associated diarrhea caused by Clostridium difficile (Beyond the Basics)
- Mayo Clinic C. difficile Infection https://www.mayoclinic.org/diseases-conditions/c-difficile/symptoms-causes/syc-20351691