ALSO KNOWN AS:
HMG-CoA reductase inhibitors
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WHAT THEY DO:
Lipid lowering medication
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EXAMPLES OF STATINS:
Atorvastatin
Fluvastatin
Pravastatin
Simvastatin
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NCLEX & OTHER TEST TAKING TIPS:
- Know signs and symptoms of rhabdomyolysis:
- Ex: Myalgias, tea colored urine, elevated CK level, Renal failure
- Know meds that increase risk to develop Rhabdo. while on a statin:
- Ex: Gemfibrizol (fibrate)-also often given for lipid lowering
- Ex: Amlodipine
- Know how statins should be taken:
- Ex: Best in pm
- Ex: Avoid taking with grapefruit juice
- Know potential affects on lab values:
- Ex: Increased A1C, ALT, AST
- Ex: If taking coumadin- INR may increase= increased risk for bleed
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