WANT THE MOST CURRENT QUESTIONS SENT TO YOU? SIGNUP:
[jetpack_subscription_form]
Are you a nursing student? New nurse? Studying for NCLEX? Nurse practitioner (or student)? Medical student? Seasoned nurse? Physician assistant (or student)? Or just love to learn about medical stuff? Med Made Ez Youtube channel is the channel for you!
Example Video:
TODAY’S TEST QUESTION:
CORRECT ANSWER:
B) They should not take NSAIDs
MORE INFO:
-
FDA has a warning statement that NSAIDs (such as ibuprofen) can actually increase the risk to have a myocardial infarction.
-
Asa is the exception and is actually recommended in MI hx to help prevent. NSAIDs elevate blood pressure and can cause heart failure (1).
-
Even short term use can create problems. Naproxen is an NSAID that also carries a risk for MI. (2)
-
Risk is highest in first few weeks of using & with higher doses (2).
-
NSAIDS cause a “relatively selective reduction in prostacyclin activity” and this can “could predispose to endothelial injury” (3), but there could be other factors “including effects on blood pressure, renal function, endothelial cells, and nitric oxide production ” that contribute -(3-Solomon, 2017).
-
Endothelial injury -cells damaged in the lining of blood vessels
- References:
1) Harvard Health Publishing
2) Medscape All Nsaids linked to Increased MI risk
3) Solomon, D. (2017) “COX-2 Selective Inhibitors: Adverse Cardiovascular effects”-Up to Date