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TODAY’S TEST QUESTION:
CORRECT ANSWER:
A) HCTZ
MORE INFO:
- Diuretics, antihistamines, and antibypertensive often predispose individuals to heat stroke.
- During heat stroke the body’s cooling mechanism becomes overwhelmed.
- The core temperature rises.
- Heat stroke is usually associated with a core temp of 40C or greater (104).
- Note that acetaminophen doesn’t usually lower temperature in individuals with heat stroke
OTHER ANSWERS
- Ativan can actually be used for heat stroke to help with sedation- as they may have convulsions and shaking.
- Phenobarbital may also be used for convulsions
OTHER PREDISPOSING MEDS & SITUATIONS:
- Drugs increasing heat production
- cocaine
- amphetamines
- ephedrine
- Drugs that decrease thirst:
- haloperidol
- Drugs that decrease sweating:
- antihistamines
- anticholinergics
- phenothiazines
- β-blockers
- Infections
- Some supplements
- Lithium
- Alcohol withdrawal
REFERENCES:
1. Helman,R. & Habal, R., (2017). Heat stroke medications. Medscape Retrieved on June 20, 2018 from https://emedicine.medscape.com/article/166320-medication#5)
2. William J. Benedetto (2013), in Critical Care Secrets (Fifth Edition)